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ZOVIRAX


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Drug Uses

Zovirax is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes healing. Topical Zovirax does not prevent the recurrence of sores but may decrease pain and itching if applied when the earliest symptoms first appear. Oral Zovirax decreases the frequency and severity of recurrent sores, but it is used only by people with severe herpes infections because of possible adverse effects. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How Taken

Treatment with Zovirax topical should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters). Wash your hands before and after applying Zovirax topical. Wear a glove or a finger cot or use an applicator (e.g. cotton swab) when applying Zovirax topical to avoid spreading the virus to other body parts and to other people. Apply enough ointment to cover the lesion(s) completely. A one-half inch ribbon of ointment should cover approximately 4 square inches of surface area. Avoid getting this medication in the eyes. Zovirax topical is usually applied every 3 hours, six times a day for seven days. Follow your doctor's instructions. Use Zovirax topical for the full amount of time prescribed, even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.

Warnings/Precautions

Before using Zovirax topical, tell your doctor if you have any other medical conditions or if you use any other medications. Zovirax topical is in the FDA pregnancy category C, which means that it is not known whether it will harm an unborn baby. Do not use Zovirax topical without first talking to your doctor if you are pregnant. It is not known whether Zovirax topical passes into breast milk. Do not use Zovirax topical without first talking to your doctor if you are breast feeding a baby.

Missed Dose

Apply it as soon as you remember and apply further doses at your regular interval (e.g., every 3 hours) until you go to bed. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Possible Side Effects

No serious side effects are expected during treatment with Zovirax topical. If you suspect an allergic reaction (difficulty breathing; rash; hives; itching; swelling of your lips, tongue, or face) seek emergency medical attention. Other less serious side effects may be more likely to occur. Continue to use Zovirax topical and talk to your doctor if you experience itching, stinging, burning, or a rash. These side effects should resolve quickly. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store below 25oC. Do not refrigerate.

Overdose

An overdose of this medication is not likely to occur. If you suspect an overdose or ingestion of Zovirax topical, call an emergency room or poison control left for advice.

More Information

Zovirax Cream is contra-indicated in patients known to be hypersensitive to acyclovir or propylene glycol. Zovirax is most effective if it is started within 48 hours of when the rash first appears. Follow the directions for using Zovirax provided by your doctor.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.




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Genital herpes is a highly contagious viral condition caused by the herpes simplex virus (HSV). It principally infects the skin and mucous membranes of the genitals and rectum, but can also appear in areas such as the mouth. It is transmitted primarily through physical and sexual contact. During birth, the presence of herpes simplex virus on the genitalia or in the birth canal is a threat to the infant. Infection in the newborn infant can lead to herpetic meningitis, herpetic viremia (herpes virus particles present in the blood) and chronic skin infection The symptoms of herpes simplex virus usually occur a week after infection, but sometimes take longer to appear. Initially, the skin becomes reddened and multiple small blisters filled with a clear, straw-coloured fluid appear. Prior to the presence of blisters, the infected individual may also experience increased skin sensitivity, tingling, burning or pain at the site where blisters will appear. Later, the blisters burst leaving shallow, painful ulcers which eventually scab and heal over a period of 7 to 14 days. The outbreak may be accompanied by other symptoms such as: # swelling and tenderness of the lymph nodes in the groin area. # in women, vaginal discharge and painful urination. # in men, a possibility of painful urination if the lesion is near the opening of the urethra. # fever. In most cases, a description of the condition and the appearance of the blisters will be enough to make a diagnosis. The GP may also advise referral to a specialist genitourinary medicine (GUM) clinic for confirmation of the diagnosis. There is no cure for the herpes simplex virus; once infected, patients will remain a carrier for the rest of their lives. Some remedies, however, can reduce the duration of the eruption. In addition, by being more aware of the initial symptoms of recurrence (skin sensitivity and tingling), timely treatment with medication such as aciclovir (Zovirax tablets/suspension) will often abort the outbreak of blisters. The best way to prevent recurrence is to avoid direct contact with an open lesion. People with herpes simplex virus should avoid sexual contact when active lesions are present. Although the symptoms of genital herpes may not be present, it is important for those infected to inform their partner that they have the disease. This will encourage both parties to use barrier protection (condoms) to prevent the spread of the illness. Using condoms and not sharing towels are good ways of reducing the chance of infection in the first place. For more information, read the factsheet on Herpes genitals.

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