Drug Uses
Diprolene AF Cream is indicated for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years and older.
How Taken
Apply a thin film of Diprolene AF Cream to the affected skin areas once or twice daily. Treatment with Diprolene AF Cream should be limited to 45 g per week.
Warnings/Precautions
This medication is to be used as directed by the physician and should not be used longer than the prescribed time period. It is for external use only. Avoid contact with the eyes. Do not use this medication for any disorder other than that for which it was prescribed. The treated skin area should not be bandaged or otherwise covered or wrapped as to be occlusive.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
Adverse reactions reported to be possibly or probably related to treatment with Diprolene AF Cream during a pediatric clinical study include signs of skin atrophy (telangiectasia, bruising, shininess).
Storage
Store between 2°and 30°C (36° and 86° F).
Overdose
Topically applied Diprolene AF can be absorbed in sufficient amounts to produce systemic effects. Seek emergency medical attention if an overdose is suspected.
More Information
Diprolene AF Cream is contraindicated for patients who are hypersensitive to betamethasone dipropionate, to other corticosteroids, or to any ingredient in this preparation.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Two proteins may help fight skin cancer
CHAPEL HILL, N.C., March 19 (UPI) -- U.S. researchers have identified two proteins that might help the body protect itself against skin cancer.
The University of North Carolina at Chapel Hill School of Medicine study indicates the proteins, named Timeless and Tipin, form a complex that regulates the rate at which DNA is replicated after exposure to ultraviolet radiation.
Ultraviolet radiation can damage skin cells and, if left unrepaired by the cell, it can cause cancerous mutations.
But before cells begin to divide, they must replicate their DNA to form new daughter cells. If damage in the DNA is discovered even after the cell has started to replicate its DNA, the Timeless/Tipin complex sends a signal that slows the replication. That slowdown, said the researchers, might give the cell additional time to repair its DNA and potentially save itself from becoming cancerous or from dying in response to ultraviolet radiation.
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