Drug Uses

Detrol LA capsules are once daily extended release capsules indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.

How Taken

Detrol LA comes as a tablet and an extended-release (long-acting) capsule to take by mouth. The tablet is usually taken twice a day. The extended-release capsule is usually taken once a day with liquids. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Detrol LA exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the extended-release capsules whole; do not split, chew, or crush them.

Warnings/Precautions

Do not take Detrol LA if you have a blockage of the urinary tract (difficulty urinating); or a blockage in the intestines. Before taking Detrol LA, tell your doctor if you have liver disease; kidney disease; or glaucoma. You may not be able to take Detrol LA, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above. Detrol LA is in the FDA pregnancy category C. This means that it is not known whether Detrol LA will be harmful to an unborn baby. Do not take Detrol LA without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Detrol LA will harm a nursing infant. Do not take Detrol LA without first talking to your doctor if you are breast-feeding a baby.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Possible Side Effects

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking Detrol LA and seek emergency medical attention. Other, less serious side effects may be more likely to occur. Continue to take Detrol LA and talk to your doctor if you experience dry mouth, dryness of the eyes, blurred vision or large pupils, upset stomach, headache, constipation, difficulty urinating, drowsiness, or dizziness. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store at controlled room temperature 20° to 25° C (68° to 77° F).

Overdose

Seek emergency medical attention. Symptoms of Detrol LA overdose are not known but might include restlessness, tremor, irritability, seizures, delirium, hallucinations, flushing, fever, nausea, vomiting, a fast heartbeat and possibly coma.

More Information

Use caution when driving, operating machinery, or performing other hazardous activities. Detrol LA may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Detrol LA. Avoid becoming overheated in hot weather. Detrol LA may increase the risk of heat stroke because it may decrease sweating. Drink plenty of fluid to maintain adequate hydration.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Heartburn Basics
What is heartburn and GERD (gastroesophageal reflux disease)? Get the facts.
Despite its name, heartburn has nothing to do with the heart (although some of the symptoms are similar to a heart attack). Heartburn, also called acid indigestion, is an irritation of the esophagus caused by acid that refluxes (comes up) from the stomach.
When swallowing, food passes down the throat and through the esophagus to the stomach. Normally, a muscular valve called the lower esophageal sphincter (LES) opens to allow food into the stomach (or to permit belching); then it closes again. Next, the stomach releases strong acids to help break down the food. But if the lower esophageal sphincter opens too often or does not close tight enough, stomach acid can reflux, or seep back into the esophagus, damaging it and causing the burning sensation we know as heartburn
Not only can stomach acid in the esophagus cause heartburn, but it can also cause esophagitis, ulcers, strictures (narrowing) and can increase the chance of cancer of the esophagus.
Most people have felt heartburn at one time or another. In fact, the American Gastroenterological Association reports that more than 60 million Americans experience heartburn/GERD symptoms at least once each month. Though uncomfortable, heartburn does not usually present a serious health problem for most people.
However, if heartburn symptoms occur frequently and persistently, they can be an indicator of a more serious problem, such as gastroesophageal reflux disease. Left untreated, GERD can cause a host of complications.
What Is Gastroesophageal Reflux Disease (GERD)?
GERD is a relatively common condition that affects from 5% to 7% of the population. It is a chronic reflux of stomach contents into the esophagus. This problem manifests itself as several symptoms including heartburn, and difficulty swallowing. Thus, if heartburn symptoms occur frequently (two or more times per week) and persistently, they are most likely caused by GERD.
The severity of GERD depends on lower esophageal sphincter dysfunction as well as the type and amount of fluid brought up from the stomach.
Treatments aim to reduce the amount of reflux or reduce the potential for damage to the esophageal lining from refluxed substances.
In addition, doctors recommend lifestyle and dietary modification to lessen acid reflux.
Causes of Heartburn
Various lifestyle and dietary factors can contribute to heartburn by relaxing the lower esophageal sphincter and allowing it to open, increasing the amount of acid in the stomach, increasing stomach pressure, or by making the esophagus more sensitive to harsh acids. These factors include:
Dietary Habits
* Eating large portions.
* Eating certain foods, including onions, chocolate, peppermint, high-fat or spicy foods, citrus fruits, garlic, and tomatoes or tomato-based products.
* Drinking certain beverages, including citrus juices, alcohol, and caffeinated and carbonated drinks.
* Eating before bedtime.
Lifestyle Habits
* Being overweight.
* Smoking.
* Wearing tight-fitting clothing or belts.
* Lying down or bending over, especially after eating.
Medical Causes
* Pregnancy
* Bulging of the stomach into the chest cavity, also called hiatal hernia.
* GERD
* Taking certain medications, especially some antibiotics and aspirin.

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