Drug Uses
Denavir is a topical antiviral medication used for recurrent cold sores (herpes labialis) on the lips and face in otherwise healthy adult patients. Denavir topical may also be used for purposes other than those listed in this medication guide.
How Taken
Apply Denavir every two hours during waking hours for four days to your cold sore with your finger or a cotton swab. Wash hands with soap and water to prevent it from coming into contact with your eyes or other areas; to prevent irritation and to prevent spread of the herpes virus.
Warnings/Precautions
Denavir is a topical cream that is applied externally on the lips and face. Do not apply Denavir on mucous membranes inside the mouth, nose, genital or rectal areas.
Denavir topical is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not use Denavir topical during pregnancy without first talking to your doctor.
It is not known whether Denavir topical passes into breast milk. Do not use Denavir topical if you are breast-feeding a baby without first talking to your doctor.
Missed Dose
Use the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and use only your next regularly scheduled dose.
Possible Side Effects
Serious side effects have not been reported with the use of Denavir topical.
Other less serious side effects may be more likely to occur. Continue to use Denavir topical and talk to your doctor if you experience: headache; local numbness or tingling where the cream is applied; changes in taste; rash; irritation at the application site.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Storage
Store at controlled room temperature, 20°-25°C (68°-77°) away from moisture and heat.
Overdose
An overdose of Denavir topical is unlikely to threaten life. If an excessive amount of the cream has been used, or if the cream has been ingested, contact a poison control left or an emergency room for advice.
More Information
Do not use other topical medications to treat the same area at them same time as Denavir topical, unless otherwise directed by your doctor.
No other medicines have been reported to interact with Denavir topical. Talk to your doctor or pharmacist before taking other prescription or over-the-counter medications during treatment with Denavir topical.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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Antiviral medications are the recommended treatment for herpes simplex virus (HSV) infection.
Medication Choices
Acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex)
The topical form of acyclovir (Zovirax ointment) offers little benefit in the treatment of genital herpes and is not recommended.
What To Think About
People taking antiviral medication every day (suppressive therapy) should discuss not taking the medication for a short period each year with their health professional. This can help determine whether genital herpes outbreaks recur as frequently. They can then decide whether they need to continue taking medication. People who have six or more outbreaks per year may benefit from taking antiviral medication every day.
Antiviral medications for genital herpes work best when they are taken as soon as symptoms are noticed. For that reason, people with herpes should keep a supply of the medication on hand.
The use of famciclovir (Famvir) and valacyclovir (Valtrex) during pregnancy has not been studied and is not recommended.
People with impaired immune systems may be more likely to:
* Need daily antiviral medication to prevent recurrent outbreaks.
* Develop a resistance to some antiviral medications. Other antivirals are available in these cases, although they must be given through a vein (intravenously, or IV) and can have dangerous side effects.
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