Drug Uses

Acyclovir is used to treat herpes infections of the skin, lip, and genitals; herpes zoster (shingles); and chickenpox. It does not cure herpes infections but decreases pain and itching and promotes healing. Sometimes acyclovir is given to help prevent the infection from coming back. Acyclovir also treats shingles and chickenpox infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How Taken

Acyclovir tablets or capsules should be taken by mouth, following the directions on the prescription label. Swallow whole with a full glass of water. Take your doses at regular intervals, with or without food, not more often than directed. Finish the full course prescribed by your prescriber or health care professional even if you think your condition is better. Do not stop taking except on your prescriber's advice. Special care may be needed for use of this medicine in children, contact your pediatrician or health professional.

Warnings/Precautions

Patients with renal impairment need dosage adjustments. Caution should also be exercised to patients receiving potentially nephrotoxic agents (this may increase the risk of renal dysfunction and/or the risk of reversible central nervous system symptoms such as those that have been reported in patients treated with intravenous acyclovir). Patients should consult with their physician if any adverse reactions occurs, also if they become pregnant or intend to become pregnant, they intend to breastfeed while taking orally administered Acyclovir, or they have any other questions.
Herpes Zoster: There are no data on treatment initiated more than 72 hours after onset of the zoster rash. Patients should be advised to initiate treatment as soon as possible after a diagnosis of herpes zoster.
Genital Herpes Infections: Acyclovir is not a cure for genital herpes.
Chickenpox: Chickenpox in otherwise healthy children is usually a self-limited disease of mild to moderate severity. Adolescents and adults tend to have more severe disease. Treatment was initiated within 24 hours of the typical chickenpox rash in the controlled studies, and there is no information regarding the effects of treatment begun later in the disease course.

Missed Dose

In case you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Possible Side Effects

Side effects depend upon the dose you are taking and the infection being treated. These side effects you should report to your prescriber or health care professional as soon as possible: confusion or hallucinations, increased thirst,redness, blistering, peeling or loosening of the skin, including inside the mouth, reduced amount of urine passed, seizures, skin rash or hives, stomach pain, tremor, unusual weakness or tiredness Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): diarrhea, dizziness, headache, increased sensitivity to the sun, loss of appetite, nausea, vomiting

Storage

Store at room temperature between 15° and 25°C (59° and 77°F). Protect from light and moisture. Keep out of the reach of children. Throw away any unused medicine after the expiration date.

Overdose

Agitation, coma, seizures, and lethargy may occur in association with overdosage. Overdosage has been reported following bolus injections or inappropriately high doses and in patients whose fluid and electrolyte balance were not properly monitored. This has resulted in elevated BUN and serum creatinine and subsequent renal failure. In the event of acute renal failure and anuria, the patient may benefit from hemodialysis until renal function is restored

More Information

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. Follow the directions for using Acyclovir provided by your doctor.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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What is the most important information I should know about valacyclovir?
finish Take all of the valacyclovir that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
Treatment with valacyclovir should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters).
Herpes infections are contagious and you can infect other people, even during treatment. Avoid letting infected areas come into contact with other people. Wash your hands frequently to prevent transmission.
Valacyclovir is not a cure for herpes virus infections.
What is valacyclovir?
Valacyclovir is an antiviral drug. It slows the growth and spread of the herpes virus so that the body can fight off the infection. Valacyclovir lessens the symptoms of these infections and shortens the length of time you are sick.
Valacyclovir is used in the treatment and suppression of genital herpes, shingles, and cold sores. Valacyclovir is not a cure for herpes virus infections.
Valacyclovir may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking valacyclovir?
donot Do not take valacyclovir without first talking to your doctor if you are allergic to acyclovir (Zovirax).
Before taking this medication, tell your doctor if you have kidney disease or immune system problems. You may need a dosage adjustment or special monitoring during treatment with valacyclovir.
Valacyclovir is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
nobrfeed It is not known whether valacyclovir passes into breast milk and how it may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
How should I take valacyclovir?
Take valacyclovir exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Treatment with valacyclovir should be started as soon as possible after the first appearance of symptoms (e.g. for cold sores-tingling, burning, blisters).
water Take each dose with a full glass of water.
Valacyclovir can be taken with or without food. Taking valacyclovir with food may decrease stomach upset.
finish Take all of the valacyclovir that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
It is important to take valacyclovir regularly to get the most benefit.
Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.
rt Store valacyclovir at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.
What happens if I overdose?
emt Seek emergency medical treatment if an overdose is suspected.
The symptoms of an overdose of valacyclovir are not well known, but an overdose of acyclovir (Zovirax), which is a similar drug, may cause seizures, hallucinations, and kidney damage (decreased urine production).
What should I avoid while taking valacyclovir?
Herpes infections are contagious and you can infect other people, even during treatment. Avoid letting infected areas come into contact with other people. Wash your hands frequently to prevent transmission.
Valacyclovir will not prevent the spread of genital herpes. Avoidance of sexual intercourse and use of latex condoms may prevent spreading the virus to others.
What are the possible side effects of valacyclovir?
emt Stop taking valacyclovir and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
Other, less serious side effects may be more likely to occur. Continue to take valacyclovir and talk to your doctor if you experience
* nausea, vomiting, diarrhea, constipation, or abdominal pain;
* headache;
* dizziness; or
* tremors.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect valacyclovir?
Probenecid (Benemid) and cimetidine (Tagamet, Tagamet HB) may increase the effects of valacyclovir and possibly lead to dangerous side effects. You may need a dosage adjustment or special monitoring during treatment if you are taking probenecid or cimetidine.
Drugs other than those listed here may also interact with valacyclovir. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

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